Numento ! The collection software •Recent publications
Carvalho K, Martin E, Ces A, Sarrazin N, Lagouge-Roussey P, Nous C, Boucherit L, Youssef I, Prigent A, Faivre E, Eddarkaoui S, Gauvrit T, Vieau D, Boluda S, Huin V, Fontaine B, Buée L, Delatour B, Dutar P, Sennlaub F, Guillonneau X, Blum D*, Delarasse C* (2021) P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy. Prog Neurobiol. 206:102139. DB corresponding author
Brigas HC, Ribeiro M, Coelho JE, Gomes R, Gomez-Murcia V, Carvalho K, Faivre E, Costa-Pereira S, Darrigues J, de Almeida AA, Buée L, Dunot J, Marie H, Pousinha PA, Blum D, Silva-Santos B, Lopes LV, Ribot JC (2021) IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer's disease. Cell Reports 236(9):109574.
Chang CP, Chang YG, Chuang PY, Nguyen TNA, Chou FY, Cheng SJ, Chen HM, Jin LW, Carvalho K, Huin V, Buée L, Liao YF, Lin CJ, Blum D*, Chern Y (2021) Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy. Acta Neuropathologica Communications (in press). DB corresponding author
Nebie O, Carvalho K, Barro L, Delila L, Faivre E, Renn TY, Chou ML, Wu YW, Niem-Redene A, Chou SY, Buée L, Hu CJ, Peng CW, Devos D, Blum D*, Burnouf T* (2021) Human platelet lysate biotherapy for traumatic brain injury: preclinical assessment. Brain. awab205. doi: 10.1093/brain/awab205. DB corresponding author
Maté de Gérando A, d'Orange M, Augustin E, Joséphine C, Aurégan G, Gaudin-Guérif M, Guillermier M, Hérard AS, Stimmer L, Petit F, Gipchtein P, Jan C, Escartin C, Selingue E, Carvalho K, Blum D, Brouillet E, Hantraye P, Gaillard MC, Bonvento G, Bemelmans AP, Cambon K (2021- Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state. Brain. 144(4):1167-1182.
Hartnell I, Blum D, Nicoll JAR, Dorothee G, Boche D (2020) Glial cells and adaptive immunity in frontotemporal dementia with tau pathology. Brain 144(3):724-745.
Carvalho K, Faivre E, Pietrowski MJ, Marques X, Gomez-Murcia V, Deleau A, Huin V, Hansen JN, Kozlov S, Danis C, Temido-Ferreira M, Coelho JE, Mériaux C, Eddarkaoui S, Le Gras S, Dumoulin M, Cellai L, NeuroCEB Brain Bank, Landrieu I, Chern Y, Hamdane M, Buée L, Boutillier AL, Levi S, Halle A, Lopes LV & Blum D. Exacerbation of C1q dysregulation, synaptic loss and memory deficits in Tau pathology linked to neuronal adenosine A2A receptors. Brain 142(11):3636-3654.
Temido-Ferreira M, Ferreira DG, Batalha VL, Marques-Morgado I, Coelho JE, Pereira P, Gomes R, Carvalho S, Canas PM, Cuvelier L, Buée-Scherrer V, Faivre E, Baqi Y, Müller CE, Pimentel J, Schiffmann SN, Buée L, Bader M, Outeiro TF, Blum D, Cunha RA, Marie H, Pousinha PA and Lopes LV (2020) The age-related shift in LTD induction is mediated by adenosine A2A receptors through NMDA receptors and Ca2+ dysregulation. Molecular Psychiatry 25(8):1876-1900
Degiorgis L, Karatas M, Sourty M, Faivre E, Lamy J, Noblet V, Bienert T, Reisert M, von Elverfeldt D, Buée L, Blum D , Boutillier AL , Armspach JP , Blanc F and Harsan LA (2020) Brain networks remodeling reflects Tau-related pathology prior to memory deficits in Thy-Tau22 mice. Brain (in press)
Sierksma A, Lu A, Salta E, Mancuso R, Zoco J, Blum D, Buee , Fiers M, De Strooper B (2020) Novel Alzheimer risk genes determine the microglia response to amyloid-beta but not to TAU pathology. EMBO Mol Med doi: 10.15252/emmm.201910606.
Paiva I*, Carvalho K*, Cellai L*, Santos P, Pavlou MAS, Jain G, Gnad T, Pfeifer A, Vieau D, Fisher A, Buée L, Outeiro TF* & Blum D* (2019) A2AR-induced transcriptional deregulation in astrocytes: an in vitro study ; Glia doi: 10.1002/glia.23688
Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt S, Saecker A, Schwartz S, Albasset S, McManus R, Tejera D, Griep A, Santarelli F, Brosseron F, Opitz S, Stunden J, Merten M, Kayed R, Golenbock D, Blum D, Latz E, Buee L & Heneka MT (2019) Innate immune activation of the NLRP3 inflammasome pathway drives tau pathology. Nature 575 (7784), 669-673.
News
I am Research Director at Inserm (Lille, France) and visiting Professor at Taipei Medical University (CBME, Taipei, Taiwan). I coordinate a research group in the Inserm laboratory « Alzheimer & Tauopathies » at UMR-S1172 (LabEx Distalz) Lille Neuroscience & Cognition (headed by Luc Buée) in Lille, France. My research focuses on the neuroglial processes involved in neurodegeneration with a particular interest towards brain/peripheral homesotasis and purinergic receptors.
Website of Luc Buée
Website of Distalz
Website of TMU, CBME
Welcome
PhD in Neurosciences
Research Director at Inserm
David Blum
